Rapid and Easy Detection of Noro-, Rotavirus, C. diff
Qualitative real-time PCR test for the detection of Noro-, Rotavirus, C. diff
Comprehensive test results with the Vivalytic Noro-, Rotavirus, C. diff test
Gastrointestinal diseases (gastroenteritis) are inflammations of the stomach and the small and large intestines. The majority of gastrointestinal diseases are caused by infectious agents, mostly viruses such as norovirus or rotavirus, but bacterial pathogens such as Clostridioides difficile (C. difficile) also play an important role.
The bacterial pathogen C. difficile causes about 15-20% of antibiotic-associated diarrheal diseases. (1) The clinical spectrum of C. difficile infection (CDI) ranges from mild diarrhea to severe, life-threatening pseudomembranous colitis. (2)
Noroviruses cause the majority of all gastrointestinal infections. They are highly contagious and therefore pose a serious problem for healthcare facilities with debilitated patients, e.g. nursing homes. (3)
Rotaviruses are the most common cause of severe diarrhea in infants and young children worldwide. During infection, many children need medical help due to high fluid loss. In addition to children, older people (60+) are also a risk group. (4)
PCR-based diagnostics that are as fast, simple and close to the patient as possible can help to make testing uncomplicated and to process the sensitive samples quickly and without a long transport route. The Vivalytic Noro-, Rotavirus, C. diff test distinguishes between the pathogens C. difficile, norovirus and rotavirus and delivers fast and precise results.
Pathogens detectable with Vivalytic Noro-, Rotavirus, C. diff
- Clostridioides difficile genes (tcdA/tcdB)
- Norovirus (genogroup I/ II)
- Rotavirus type A
Vivalytic Noro-, Rotavirus, C. diff – Fast laboratory testing for outbreak containment
- Only a few steps from sample to result
- No further laboratory equipment needed
- Reduced risk of infection for the user
(1) RKI Ratgeber C. difficile https://www.rki.de/DE/Content/Infekt/EpidBull/Merkblaetter/Ratgeber_Clostridium.html#doc2393684bodyText12, abgerufen am 16.06.2023
(2) https://www.ecdc.europa.eu/en/clostridium-difficile-infections/facts
(3) https://www.ecdc.europa.eu/en/norovirus-infection/facts
(4) https://www.ecdc.europa.eu/en/rotavirus-infection/facts
The advantages at a glance
Vivalytic stands for high efficiency and safety with minimum effort. The unique Vivalytic platform provides ideal assistance for everyday work in clinics, practices, and laboratories.
Comprehensive results
The Vivalytic Noro-, Rotavirus, C. diff test utilises a two target approach to detect different pathogens.
High usability
The minimalistic design, easy handling and comprehensive depiction of the results ensure a high level of usability.
Easy handling
Like all Vivalytic tests, the Vivalytic Noro-, Rotavirus, C. diff test is fully automated. This allows for fewer work steps, saving valuable time.
Only few steps from sample to result
What exactly happens in the Vivalytic Analyser?
The Vivalytic Analyser automates complex, molecular diagnostic processes that previously had to be carried out manually. This promotes high safety and quick availability of the test results.
| 1. Step | 2. Step | 3. Step | 4. Step | 5. Step |
|---|---|---|---|---|
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1. Step
Preparing the sample
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2. Step
Cell lysis
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3. Step
Extraction of the nucleic acid
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4. Step
DNA amplification
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5. Step
Bio-analytical detection
|
1. Step
|
2. Step
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3. Step
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4. Step
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5. Step
|
|
1. Step
Samples are processed reliably.
|
2. Step
The external membrane of the cells is broken down through ultrasound.
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3. Step
The nucleic acid (DNA/RNA) is purified for the PCR amplification.
|
4. Step
Specific DNA sequences are multiplied using PCR.
|
5. Step
The amplified DNA is identified by detecting a fluorescence or chemiluminescence signal.
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